A Rab6 to Rab11 transition is required for dense-core granule and exosome biogenesis in Drosophila secondary cells.
Secretory cells in glands and the nervous system frequently package and store proteins destined for regulated secretion in dense-core here granules (DCGs), which disperse when released from the cell surface.Despite the relevance of this dynamic process to diseases such as diabetes and human neurodegenerative disorders, our mechanistic understanding